Maintenance chemotherapy for non-small-cell lung cancer
نویسندگان
چکیده
منابع مشابه
Maintenance chemotherapy for non-small-cell lung cancer.
Currently, platinum-based combination chemotherapy is the standard first-line chemotherapy for non-small-cell lung cancer (NSCLC). Historically, platinum-based chemotherapy has been recommended for up to six cycles even for responders, and second-line chemotherapy has been considered when disease progression is confirmed. In spite of extensive investigations into maintenance chemotherapy, no po...
متن کاملMaintenance chemotherapy in non-small cell lung cancer.
Recent trials have shown a benefit with maintenance therapy after 4 to 6 cycles of chemotherapy. These trials have shown improvement in progression-free survival using agents approved as second-line therapy in non-small cell lung cancer. Trials using erlotinib and pemetrexed showed improvement in overall survival. Consideration of trial design is critical for the interpretation of these results...
متن کاملMaintenance Chemotherapy Use for Advanced Non-Small Cell Lung Cancer in an Australian Cancer Centre
Background To investigate the rates of maintenance therapy in advanced non-small cell cancer, the reasons for not progressing to second line therapy at disease progression at our cancer centre and to use this data as a way to institute it into clinical practice in our cancer centre. Method This study was approved by the ethics committee. The data was collected from a purpose built cancer unit...
متن کامل[Maintenance therapy for advanced non-small-cell lung cancer].
Maintenance therapy is a new treatment strategy for advanced non-small-cell lung cancer(NSCLC), and it consists of switch maintenance and continuation maintenance.Switch maintenance is the introduction of a different drug, not included as part of the induction therapy, immediately after completion of 4 cycles of first-line platinum-based chemotherapy.Continuation maintenance is a continuation o...
متن کاملMaintenance Therapies for Non-Small Cell Lung Cancer
Treatment of lung cancer had evolved during the last decade with the introduction of new chemotherapeutic regimens and targeted therapies. However, the maximum benefit reached after first-line therapy is limited by the cumulative toxicity of platinum drugs and the subsequent deterioration in performance status in a high percentage of patients who end up receiving not more than one line of treat...
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ژورنال
عنوان ژورنال: Cancer Treatment Reviews
سال: 2011
ISSN: 0305-7372
DOI: 10.1016/j.ctrv.2010.12.007